Sigma Xi 2015 Student Research Showcase

Physiology & Immunology


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ASHRAF"Deletion of Integrin Associated Protein CD47 Decreases Beta-Cell Proliferation in Mice Fed High Fat Diet"
Sidikha Ashraf, The Bronx High School TwitterIconsmThrough the years islet transplants are being improved by researchers who isolate and recognize the cellular mechanisms involved in Beta-cell proliferation. To contribute I took the pioneer step of determining the significance of a ligand to beta-cell pro 


yiChen"Examining the role of IL-2 receptor mediated signalling in Alopecia Areata"
Yi Chen, The Bronx High School

For my project, I examined the specific pathways and molecular mechanisms involved in the development of an autoimmune disease called Alopecia Areata.





AaronCarlKennethLucander"The Mechanistic Basis for Recombinase Upregulation in CD4+CD8+ Thymocytes"
Aaron Carl Kenneth Lucander, North Carolina School of Science and Mathematics

This project further characterized the genetic mechanisms underlying RAG1 and RAG2 upregulation during the CD4+CD8+ stage of thymocyte development, which have important implications for T-cell development and the existence of a functional immune system.

MarielFerragamo"Circadian activity patterns of inbred and outbred mice strains."
Mariel Ferragamo, St. Peter High School

I compared an inbred mouse strain with an outbred mouse strain to determine the precision with which they adjusted their circadian rhythms to changes of light schedule by measuring running wheel activity.



Amanda Valentine Scampini"The Effects of Stress on Learning and Memory in Bumblebees"
Amanda Valentine Scampini, University of Nevada, Reno LinkedInThe presentation will consist of a walk through for the mechanisms we have used to harness, train, and stress bumblebees. As well as discussing the three experiments that were designed to look at the affects of stress. The experiments look at long and shor 

AaditPragneshShah"Glioblastoma Induces Immunosuppression via Regulatory T Cells, PDL1, and CTLA4"
Aadit Pragnesh Shah, Illinois Mathematics and Science Academy

My research deals with Glioblastoma Multiforme, a grade IV cancer of the glial cells within the nervous system, and its immunosuppressive factors.
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JayKSharma"The effects of sLOX-1 on Diabetes Mellitus Peripheral Neuropathy Type 2"
Jay K. Sharma, Henry Wise Wood High School TwitterIconsmMy project title is in the top left area and my description with my picture is in the top right area. My video is first on my home page, with a description beneath it and a title above it. My abstract is directly beneath it, and my technical slide show pr 



TigerYunjiawuTeng"Acrolein's Effect on IL-1b-dependent Regulation on Lung gd T-cells"
Tiger Yunjiawu Teng, DuPont Manual High School

This study is to see if IL-1β is important in regulating lung γδ T cells with a focus on Vγ6, both in frequency and IL-17 production.


RashmiThimmapuram“Novel Method to Localize the Language Region using Electrocorticography (ECoG) during Natural Conversation"
Rashmi Thimmapuram, Illinois Mathematics and Science Academy

For epileptic patients, identifying the function of brain region that is causing seizures is critical in making a decision on its surgical removal. My research focused on finding patient-friendly method to identify the language region in epileptic patien 

Upadhyayula"The Effect of Mutations on an Individual’s Response to Clopidogrel using Big Data"
Sushil Baalaji Upadhyayula, Illinois Mathematics and Science Academy
Pranav Aadithya Upadhyayula, Illinois Mathematics and Science Academy

The purpose of this experiment is to identify whether certain gene mutations in proteins that interact with the drug Clopidogrel (Plavix) cause individuals to react differently to Clopidogrel. Clopidogrel is a blood thinner used to prevent stroke, heart a 















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